Evaluation of various factors relating to intraocular pressure and C/D ratio

Introduction: Intraocular pressure (IOP) is determined by three factors: the rate of aqueous humor production by the ciliary’s body, the resistances to aqueous out flow across the trabecular meshwork and the level of episcleral vessel pressure. IOP varies with a number of factors, including: age, sex, race, systemic disease and diurnal variation. The purpose of this study is measurement of IOP and C/D ratio in normal population. Methods: 200 persons who accompanied the patients referring to Shahid Mohammadi clinic underwent total eye examination, measure of IOP and C/D ratio. The obtained data was then subject to Chi-Square test and Pearson Correlation Coefficient analysis (p<0.05). Results: In statistical result, IOP>14 in the left eyes of persons with history of familial glaucoma was more than persons without familial glaucoma (p<0.01). the same result was attained for the right eyes. Also C/D ratio was higher in persons with glaucoma familial history (p<0.01). There was a positive correlation between age and right eye IOP (r=0.37) and left eye IOP (r=0.41) also there was a positive correlation between age and C/D ratio. Conclusion: Age has an important effect on increasing IOP and C/D ratio in both eyes, no difference between myopic and non myopic persons in IOP & C/D ratio, and there is not any effect of myopic on IOP and C/D ratio. The study suggested familial history of glaucoma has an important effect on increasing IOP and C/D ration in both eyes.